Mariko Harada-Shiba Selected Research

pitavastatin (itavastatin)

5/2018	Efficacy and Safety of Pitavastatin in Children and Adolescents with Familial Hypercholesterolemia in Japan and Europe.
1/2016	Efficacy and Safety of Pitavastatin in Japanese Male Children with Familial Hypercholesterolemia.

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Mariko Harada-Shiba Research Topics

Disease

41	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 09/2023 - 12/2008
24	Atherosclerosis 04/2024 - 06/2003
23	Cardiovascular Diseases (Cardiovascular Disease) 03/2024 - 01/2012
18	Homozygous Familial Hypercholesterolemia 01/2024 - 08/2003
17	Coronary Artery Disease (Coronary Atherosclerosis) 12/2023 - 07/2010
13	Xanthomatosis (Xanthoma) 10/2022 - 06/2003
9	Inborn Genetic Diseases (Disease, Hereditary) 05/2024 - 01/2012
8	Dyslipidemias (Dyslipidemia) 03/2024 - 01/2012
6	Hyperlipoproteinemia Type III (Broad Beta Disease) 06/2022 - 06/2003
6	Hypercholesterolemia 01/2018 - 06/2003
5	Stroke (Strokes) 12/2021 - 04/2015
4	Coronary Disease (Coronary Heart Disease) 09/2023 - 09/2006
4	Diabetes Mellitus 07/2023 - 06/2019
4	Acute Coronary Syndrome 12/2021 - 01/2017
4	Inflammation (Inflammations) 01/2020 - 03/2010
3	Myocardial Infarction 02/2024 - 02/2007
3	Hypertension (High Blood Pressure) 11/2022 - 08/2021
3	Hypertriglyceridemia 10/2022 - 06/2008
3	Neoplasms (Cancer) 01/2018 - 12/2012
3	Ischemia 01/2014 - 02/2004
2	Retinitis Pigmentosa (Pigmentary Retinopathy) 05/2024 - 10/2021
2	Abetalipoproteinemia (Bassen Kornzweig Syndrome) 05/2024 - 10/2021
2	Type 2 Diabetes Mellitus (MODY) 01/2023 - 01/2018
2	Carotid Artery Diseases 06/2022 - 01/2017
2	Hyperuricemia 11/2021 - 01/2020
2	Hemorrhage 10/2021 - 01/2017
2	Anemia 10/2021 - 07/2021
2	Body Weight (Weight, Body) 01/2019 - 05/2018
2	Necrosis 01/2019 - 02/2004
2	Atherosclerotic Plaque (Atheroma) 01/2019 - 03/2017
2	Brain Injuries (Brain Injury) 01/2018 - 04/2015
2	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2018 - 01/2016
2	Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain) 01/2016 - 04/2015
2	Breast Neoplasms (Breast Cancer) 10/2013 - 12/2012
2	Neoplasm Metastasis (Metastasis) 10/2013 - 12/2012
2	Pulmonary Hypertension 07/2009 - 08/2003
1	Growth Disorders 05/2024
1	Hypobetalipoproteinemias (Hypobetalipoproteinemia) 05/2024
1	Acquired Immunodeficiency Syndrome (AIDS) 03/2024

Drug/Important Bio-Agent (IBA)

45	oxidized low density lipoproteinIBA 04/2024 - 08/2003
34	LDL CholesterolIBA 12/2023 - 06/2008
23	LipidsIBA 03/2024 - 05/2006
20	LDL Lipoproteins (beta Lipoproteins)IBA 10/2022 - 08/2003
16	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 04/2024 - 07/2010
16	LDL Receptors (LDL Receptor)IBA 01/2023 - 06/2003
14	Lipoproteins (Lipoprotein)IBA 05/2024 - 05/2006
11	CholesterolIBA 02/2024 - 08/2003
8	ApolipoproteinsIBA 05/2024 - 01/2013
8	HDL CholesterolIBA 04/2024 - 06/2008
6	Apolipoproteins B (ApoB)IBA 05/2024 - 01/2013
6	BMS201038IBA 01/2024 - 04/2017
5	HDL LipoproteinsIBA 03/2024 - 01/2012
5	Proprotein Convertase 9IBA 01/2021 - 01/2013
5	Proteins (Proteins, Gene)FDA Link 01/2017 - 09/2006
5	Small Interfering RNA (siRNA)IBA 04/2014 - 11/2009
4	Triglycerides (Triacylglycerol)IBA 04/2024 - 01/2012
4	Atorvastatin (Lipitor)FDA Link 04/2024 - 08/2003
4	Biomarkers (Surrogate Marker)IBA 12/2023 - 01/2016
4	Ezetimibe (Zetia)FDA Link 07/2023 - 05/2006
4	alirocumabIBA 01/2020 - 12/2015
3	VitaminsIBA 05/2024 - 01/2019
3	microsomal triglyceride transfer proteinIBA 05/2024 - 07/2017
3	Proprotein Convertases (Pro-Opiomelanocortin Converting Enzyme)IBA 10/2019 - 01/2015
3	SubtilisinIBA 10/2019 - 01/2015
3	Therapeutic UsesIBA 08/2019 - 04/2015
3	Apolipoproteins E (ApoE)IBA 04/2019 - 01/2013
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2017 - 12/2012
3	CeramidesIBA 01/2013 - 09/2006
2	O(4)-methylthymidine triphosphateIBA 05/2024 - 10/2021
2	ChylomicronsIBA 05/2024 - 01/2012
2	Rosuvastatin Calcium (Crestor)FDA Link 04/2024 - 01/2018
2	Glucagon-Like Peptide-1 Receptor AgonistsIBA 01/2023 - 01/2018
2	Lipoprotein(a)IBA 08/2022 - 01/2022
2	AcidsIBA 04/2022 - 02/2010
2	FurinIBA 12/2021 - 01/2015
2	omega-Chloroacetophenone (Mace)IBA 12/2021 - 01/2017
2	Uric Acid (Urate)IBA 11/2021 - 01/2020
2	EnzymesIBA 09/2021 - 07/2021
2	Monoclonal AntibodiesIBA 12/2020 - 12/2015
2	CytokinesIBA 04/2019 - 06/2012
2	SonazoidIBA 01/2019 - 01/2018
2	Conditioned Culture MediaIBA 01/2019 - 01/2014
2	pitavastatin (itavastatin)FDA Link 05/2018 - 01/2016
2	Nucleic AcidsIBA 12/2017 - 09/2012
2	Antisense OligonucleotidesIBA 12/2017 - 09/2016
2	Dextran SulfateIBA 01/2017 - 11/2016
2	Vascular Endothelial Growth Factor CIBA 10/2013 - 12/2012
2	AdrenomedullinIBA 07/2009 - 02/2004
2	MonocrotalineIBA 07/2009 - 08/2003

Therapy/Procedure

23	Therapeutics 04/2024 - 08/2003
15	Blood Component Removal (Apheresis) 12/2021 - 08/2003
3	Drug Therapy (Chemotherapy) 05/2023 - 04/2017
3	Transplantation 01/2014 - 08/2003
2	Renal Dialysis (Hemodialysis) 11/2021 - 07/2021
2	Fat-Restricted Diet (Diet, Fat Restricted) 04/2019 - 01/2019
2	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2018 - 01/2013
2	Intravenous Administration 01/2018 - 01/2016
2	Injections 10/2013 - 12/2012
1	Patient Transfer (Patient Dumping) 03/2024
1	Transitional Care 03/2024